Additional information?

Isoxazolines are valued for their rapid onset of action, efficacy, and duration of protection against fleas and ticks.

Risks to Dogs?

Although the toxicity of isoxazolines is supposed to affect invertebrates only, there are many reports of dogs being severely impacted. Dogs exhibited signs of neurological toxicity, including generalized loss of muscle coordination (ataxia), tremors of the head and body, muscle twitching, and swallowing difficulties.

Common Name Brands?

One of the most well-known isoxazoline-based pet products is Bravecto®, which contains fluralaner as its active ingredient. Other common brands that contain isoxazoline compounds include NexGard®, Simparica®, and Credelio®.